Luna’s Distal Limb Wound


AniCell’s StemWrap Amnion used to manage distal-limb leg injury

Warning! This case study contains pictures that are of a graphic nature.

AniCell is a biotech company that extends the ACTIVE life of animals using amniotic material to create all-natural regenerative treatments for veterinarians to treat tissue-related injuries.  Unlike our service-based competitors who harvest tissue by creating wounds to cure wounds or big Pharma drugs which treat symptoms, AniCell produces, with no harm to animals, affordable, field-ready amnion products available the same day as diagnosis.

Case Description – Leg Injury due to trailer accident

A Thoroughbred mare named Luna was on her way home from a horse show when she became upset in the trailer and began kicking and thrashing violently.  She severely injured her left hind leg, just above the hock on the lateral portion of the leg and just below the hock on the medial left hind leg.  Dr. Deanna Gazzero from Southwest Equine was on call for emergencies and immediately stitched up the wound on the evening of November 8, 2015 in an effort to save the tissue.  Luna’s regular veterinarian, Dr. James Foley, treated the wound with AniCell’s StemWrap and StemWrap Plus amnion products.

Initial injury November 12, 2015 – Day 1 after suturing by Dr. Deanna Gazzero 

Luna was treated the day after the injury by Dr. Foley with StemWrap Plus in an effort to keep the tissue from devitalizing.

Follow-up treatment with StemWrap Plus after suturing – Nov.12, 2015

Unfortunately, Luna’s leg tissue became necrotic and devitalized tissue began to sluff.

Day 5 inspection after injury – Nov.16, 2015

Day 7 follow-up shows the impact of the StemWrap Plus treatment under the devitalized tissue and the lack of infection.  Yellow tinge (exudate) of the tissue is the result of the amnion.

Day 7 inspection after injury – Nov.18, 2015

Finally on November 20 (Day 9), the wound has totally sluffed devitalized tissue.  Wound is debrided to treat with AniCell’s StemWrap Amnion biological bandage.  Medial view shows the opening of two holes just under the hock.  Only enough StemWrap product to treat the upper hole.

Lateral wound is debrided to place StemWrap bio-bandage.




On November 25, Luna showed significant wound improvement to the lateral areas treated with AniCell’s StemWrap amnion biological bandage.  Expectantly, Luna’s medial aspect shows the hole treated with amnion is completely closed with tissue in 5 days while the untreated hole continues to expand.

Day 5 inspection after partial treatment with StemWrap Amnion Biological Bandage

Nov. 30, 2015 – Day 10


Follow-up inspection on the November 30, eighteen days after the injury and shows medial wound contraction of the area’s treated with StemWrap.  The untreated hole continues to expand to 1.25″ wide and .75″ deep.  Dr. Foley treats the remaining would with a 5x5cm StemWrap by placing the wadded up amnion in against the exposed bone at the back of the wound.  Radio graphs show sequestrum forming on the medial aspect of the exposed bone.  The bone may have to be exposed to excise the devitalized bone. Lateral wound aspect continues to improve illustrating both contraction and reduced swelling after 5 days of placement of amnion.

Follow-up Checks after Amnion Placement – December 4, 2015

Four days after treating a 1.25″ wide and .75″ deep hole with a wadded-up piece of amnion, 1.1 cubic inches of tissue grew to fill the hole that had continued to grow untreated.  New radio graphs illustrated that the sequestrum that was forming due to the exposed was now normal.  Lateral wound aspect continues to improve showing a contraction of 10% after 9 days after amnion placement.

Day 10 Inspection Post Treatment #2 StemWrap (Day 28 total) – 12/09/15

Day 17 Inspection Post Treatment #2 StemWrap (Day 35 total) – 12/15/15

Wound continues to heal without the need of additional treatments.




















Day 22 Inspection Post Treatment #2 StemWrap (Day 40 total) – 12/21/15

Laterial wound left unwrapped.  Typically would leave wound wrapped until healed.

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